A Clinical Decision Rule to Predict Intracranial Hypertension in Severe Traumatic Brain Injury

What is it about?

While existing guidelines support the treatment of intracranial hypertension in severe traumatic brain injury (TBI), it is unclear when to suspect and initiate treatment for high intracranial pressure (ICP). The objective was to derive a clinical decision rule that accurately predicts intracranial hypertension.

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Why is it important?

A simple clinical decision rule based on a combination of clinical and imaging findings was found to be highly sensitive in distinguishing severe TBI patients who would suffer intracranial hypertension. It could be used to identify patients who require ICP monitoring in high-resource settings or start ICP lowering treatment in environments where resource limitations preclude invasive monitoring.