What is it about?
We intended to draw attention to the endocrine effects generated by compartmental glucocorticoid treatments
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Why is it important?
Corticosteroid therapy is used by 1% of world population, especially for non-endocrinological indications. Compartmental administration (i.e. topical, inhaled or intraarticular) was developed to prevent undesired effects. Still even these therapies could generate major endocrine syndromes.
Perspectives
This data must lead the practitioners using topical or inhaled glucocorticoids to an increased alertness level toward the possibility that even compartmental administration could cause significant systemic endocrine effects, as our two cases tend to illustrate.
Gheorghe Serpoi
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This page is a summary of: Adrenal Suppression and Exogenous Cushing Syndrome After Inhaled and Topical Corticosteroids - Two Clinical Cases and Review of the Subject, Medicina Moderna - Modern Medicine, June 2018, CMMB-Colegiul Medicilor Municipiul Bucuresti,
DOI: 10.31689/rmm.2018.25.2.95.
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