Anticancer activity of Indian Tamarisk against chemical Carcinogenesis in mice

What is it about?

The objective of the current investigation was to identify a superior alternative to the treatment for cutaneous cancer. The skin cancer was induced in mice using DMBA & croton oil. The aerial parts of Tamarix indica were extracted using methanol and water. The obtained extracts were tested for anticancer activity using a two-stage carcinogenesis model in mice. To test the efficacy of the extracts, various morphological and biochemical parameters were evaluated and tested for significance level (p<0.5). The methanol extract showed significant effects on both parameters. This proved the ethnomedicinal value of the methanol extract of the plant and paved a way for the researcher to find particular phytoconstituents and specific mechanisms of action.

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Photo by Rasa Kasparaviciene on Unsplash

Photo by Rasa Kasparaviciene on Unsplash

Why is it important?

Skin cancer is a very common problem in USA, Sweden, etc. although the diagnosis rate is very low. This is increasing social stigma and financial burden on the society. This increase the urge for new therapy with low cost and side effects. The aerial extract of the plant found having potential antioxidant as well as anticancer activity. Thus, the extracts may be very helpful in prevention or progression of the skin cancer. The particular phytoconstituent as well as specific mechanism is still to be identified and can be a better alternate to the present therapies available.

Perspectives