What is it about?
The generation of ox LDL has been linked to atherosclerosis. Patients with autoimmune disease have an increase probability of dyslipidemia and atherosclerosis. The aim of the study was to analyze the uptake of ox-LDL in monocytes from peripheral blood of SLE patients in order to propose a mechanism of atherogenesis
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Why is it important?
It opens the question on different mechanism that would explain the increase in atherosclerosis risk in SLE patients.
Perspectives
Antibodies and conjugates may increase the effect of ox LDL uptake and atheroscleris in SLE patients
Dr Juan B De Sanctis
Univerzita Palackeho v Olomouci
Read the Original
This page is a summary of: Atherosclerosis development in SLE patients is not determined by monocytes ability to bind/endocytose Ox-LDL, Autoimmunity, January 2011, Taylor & Francis,
DOI: 10.3109/08916934.2010.530626.
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