Rising Hemoglobin A1c in the Nondiabetic Range Predicts Progression of Type 1 Diabetes As Well As Oral Glucose Tolerance Tests

What is it about?

A 10% or greater change in HbA1c over time is a promising early indicator to assess escalating risk in individuals at high-risk for type 1 diabetes from both the general population and those with a family history. Incorporating regular monitoring of a change in HbA1c in those at-risk for type 1 diabetes into periodic islet autoantibody surveillance has great practicality for multiple autoantibody monitoring by primary clinicians.

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