Adult-Onset Type 1 Diabetes: Current Understanding and Challenges

What is it about?

More than half of all new cases of type 1 diabetes occur in adults. Key differences exist between adult and childhood-onset type 1 diabetes, many of which are not well-understood by the clinical and research communities. Here, we review the epidemiology, genetic, immune, and metabolic characteristics of adult-onset type 1 diabetes and highlight disease-associated comorbidities and psychosocial challenges unique to this population.

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