Metformin Affects Gut Microbiome Composition and Function and Circulating Short-Chain Fatty Acids: A Randomized Trial

What is it about?

Metformin and weight loss have been linked to changes in gut physiology. We examined and found that metformin, but not behavioral weight loss, impacted gut microbiota composition and function. Metformin also altered SCFA concentrations, including an increase in acetic acid that was associated with improved insulin sensitivity.

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