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In a longitudinal observational study of children with type 1 diabetes and age-matched non-diabetic controls followed up to 4 time-points over 8 years, we observed differences in brain volume and slower brain growth, as well as lower verbal IQ in the diabetic cohort compared to controls. These differences persisted over time and were related to the higher blood sugars. Our data support the notion that type 1 diabetes may be detrimental to the developing brain.
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This page is a summary of: Impact of Type 1 Diabetes in the Developing Brain in Children: A Longitudinal Study, Diabetes Care, February 2021, American Diabetes Association,
DOI: 10.2337/dc20-2125.
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