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By meta-analysis, we find that long-acting GLP-1 receptor agonists better reduce HbA1c, fasting plasma glucose, and body weight, when added to basal insulin treatment, in comparison to short-acting compounds, at a lower risk for gastro-intestinal side effects and hypoglycemia.

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This page is a summary of: Efficacy and Safety of Short- and Long-Acting Glucagon-Like Peptide 1 Receptor Agonists on a Background of Basal Insulin in Type 2 Diabetes: A Meta-analysis, Diabetes Care, August 2020, American Diabetes Association,
DOI: 10.2337/dc20-0498.
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