Cardiac Resynchronization for Diabetic Heart Failure Patients

What is it about?

The CARE-HF trial analyzed the effect of cardiac resynchronization therapy (CRT) on morbidity and mortality in patients with heart failure and left ventricular systolic dysfunction. Diabetes was found to be a strong predictor of mortality in these patients, and insulin use was associated with a higher mortality rate, regardless of the presence or absence of ischemic heart disease. CRT was equally effective in reducing mortality and improving outcomes in diabetic patients compared to those without diabetes. [Some of the content on this page has been created by AI]

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Why is it important?

This research is important because it analyzes the impact of diabetes and insulin use on the prognosis of patients with heart failure. It demonstrates that patients with heart failure and diabetes treated with insulin have a significantly worse prognosis than those without diabetes. Furthermore, the study shows that cardiac resynchronization therapy (CRT) is equally effective in reducing mortality and improving clinical outcomes in diabetic patients compared to those without diabetes. This information can help healthcare professionals make more informed decisions regarding the treatment of patients with heart failure and diabetes. Key Takeaways: 1. Patients with heart failure and diabetes treated with insulin have a markedly worse prognosis than those without diabetes. 2. CRT is equally effective in reducing mortality and improving clinical outcomes in diabetic patients compared to those without diabetes. 3. Diabetes, regardless of the therapy used to treat it and the presence of coronary artery disease, does not influence the beneficial effect of CRT on any endpoint.