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T cells recognizing hybrid insulin peptides have been linked to destruction of β-cells in type 1 diabetes. A new study reports that T cell responses to a broad repertoire of hybrid peptides generated from C-peptide fragments are detected in the blood of individuals at-risk for type 1 diabetes.
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This page is a summary of: Expanding the Case for Hybrid Insulin Peptides in Type 1 Diabetes, Diabetes, May 2025, American Diabetes Association,
DOI: 10.2337/dbi25-0008.
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