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We studied over 4,000 people at risk for type 1 diabetes and found that genes linked to type 2 diabetes also influence how much insulin the pancreas makes and how quickly type 1 diabetes develops. These findings show that both type 1 and type 2 genetic factors shape disease progression and point to new opportunities to improve prediction and prevention.

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This page is a summary of: Type 2 Diabetes Genetic Risk and Type 1 Diabetes Heterogeneity and Progression, Diabetes, December 2025, American Diabetes Association,
DOI: 10.2337/db25-0711.
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