Neuroligin-3: A Novel Exercise-Induced Secreted Factor Enhancing Insulin Sensitivity in Obese Insulin-Resistant Mice

What is it about?

Exercise improves metabolism, but the molecules responsible are not fully known. This study identifies Neuroligin-3 (NLGN3) as an exercise-induced factor that improves insulin sensitivity and reduces inflammation through NRXN1/3 signaling, highlighting NLGN3 as a potential target for treating obesity-related insulin resistance.

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