DNA Methylation Biomarkers Predict Offspring Metabolic Risk From Mothers With Hyperglycemia in Pregnancy

What is it about?

Children born to mothers with high blood sugar during pregnancy are at increased risk of developing diabetes later in life. This study found that specific DNA changes in newborn cord blood, called DNA methylation markers, can predict future problems with insulin-producing cells more accurately than birthweight or other clinical measures. These findings suggest that early-life blood tests may help identify children at risk for diabetes before symptoms appear.

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