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Excessive iron intake has been linked to diabetes risk. We examined the role of the hemoglobin haptoglobin receptor, CD163, in iron homeostasis. We found CD163 is protective from severe insulin resistance upon obesity only in male mice.

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This page is a summary of: Deficiency of the Hemoglobin-Haptoglobin Receptor, CD163, Worsens Insulin Sensitivity in Obese Male Mice, Diabetes, September 2024, American Diabetes Association,
DOI: 10.2337/db24-0405.
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