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The hormone glucagon normally lowers the hepatic secretion of lipids to the blood. This study shows that glucagon does not function normally in individuals with obesity-related fatty liver disease, perhaps adding to the elevated plasma lipids and cardiovascular risk in these individuals.
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This page is a summary of: Impaired Glucagon-Mediated Suppression of VLDL-Triglyceride Secretion in Individuals With Metabolic Dysfunction–Associated Fatty Liver Disease (MAFLD), Diabetes, August 2022, American Diabetes Association,
DOI: 10.2337/db22-0313.
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