Next-Generation HLA Sequence Analysis Uncovers Seven HLA-DQ Amino Acid Residues and Six Motifs Resistant to Childhood Type 1 Diabetes

What is it about?

Genetic analysis of HLA sequence data shows that seven amino-acid residues on HLA-DQ molecules and their six motifs associate with the reduced risk of type 1 diabetes among young children, and diseased carriers of these motifs appear to have normal or reduced autoantibody levels.

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