What is it about?

5-PAHSA is a lipid that helps with glucose uptake into fat cells, but in a different way from insulin.

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Why is it important?

New mechanism of 5-PAHSA action in adipocytes was discovered using metabolic flux analysis, metabolomics and lipidomics.

Perspectives

5-PAHSA is only one molecule from a huge family of FAHFAs.

Ondrej Kuda
Institute of Physiology of the Czech Academy of Sciences

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This page is a summary of: Lipokine 5-PAHSA is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for de novo Lipogenesis in Mice, Diabetes, December 2019, American Diabetes Association,
DOI: 10.2337/db19-0494.
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