Research Into Potential Therapies Against COVID-19, With Focus On Ivermectin

What is it about?

Purpose: Ivermectin is a broad-spectrum antiparasitic and an effective drug to treat COVID-19. In this article, we looked at the effects of ivermectin on coronavirus and its patients in three ways. We have discussed and organized other previously discovered potential therapies and reviewed them in Table 2 and in the last section. Methods: We searched for articles on MedRxiv, PubMed, Google Scholar, MEDLINE, EMBASE uses the appropriate search terms. ClinicalTrials.gov was searched for available clinical trials evaluating the effectiveness of ivermectin. We also use EU clinical trial registry data and ANZ registry data for clinical trials. Also, we performed our methods in 4 stages: Identifying studies, Selection of Studies, Collating Studies, Reporting results. Results: Results are variable. Some studies have shown the effectiveness of ivermectin, others have not. Furthermore, some studies show that a combination of ivermectin with other drugs is useful. Conclusion: Overall, we believe the reason ivermectin is useful is that it goes back to its origin, which is soil. Our theory and hypothesis is that if the coronavirus, created by man or by nature, can generally be treated with nature, that is, the soil. The interesting thing is that today we know that ivermectin is effective in the fight against the coronavirus. In fact, other drugs like teicoplanin, cyclosporine and rapamycin that are effective against the coronavirus have come from the soil. We hope that this article has been able to take a step in finding a corona drug, InshaAllah.

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Photo by Claire Mueller on Unsplash

Photo by Claire Mueller on Unsplash

Why is it important?

In general, it should be noted that you need to do the previously mentioned test to determine whether ivermectin is effective or not. In fact, one needs to increase the statistical population to prove that this drug does not have placebo properties. An experiment should be created where there are two groups, and the first group should receive the same drug, and it should be said that it is a drug and does not have many therapeutic properties. The second group should receive the same drug and patients should be informed that this drug has therapeutic properties. If this drug (Ivermectin) is a useful drug for coronavirus, it should be useful for both, otherwise it's just a placebo. But the interesting thing is that ivermectin originated in the soil in the first place. Professor Satoshi Omura isolated an unusual Streptomyces bacterium in soil with William Campbell in 1975 and discovered that the bacterial culture could cure mice infected with the roundworm Heligmosomoides polygyrus. Campbell isolated the active ingredients from bacterial culture and named them "avermectins" (Crump and Omura, 2011).

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