What is it about?
The transdermal route has drawn considerable attention and has emerged as a solid alternative to mimic the drawbacks of drugdelivery through the oral and parenteral routes. However, the effectiveness of TDDS is often limited by the skin's outermost layer, the stratumcorneum (SC), which acts as a barrier to drug diffusion. In addition, the drug molecule's molecular weight, hydrophilicity, and ionic nature canalso impact its transdermal delivery.
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Why is it important?
This review summarizes a combination of all different novel penetration enhancement techniques used to enhance the efficacy of transdermal drug delivery systems that were not precisely captured by other review articles. Most of the review articles emphasized these penetration enhancement techniques separately. However, a careful review of all the penetration enhancement techniques in one article is missing.
Perspectives
The purpose of this article is to comprehensively review and summarize the recently used penetration enhancement techniques along with the possible mechanism of action in a single article. Our primary aim is to collect relevant reviews and research articles by searching various databases to provide a comprehensive overview of the field.
Dr Abikesh Prasada Kumar Mahapatra
Read the Original
This page is a summary of: Increasing Efficiency of Transdermal Drug Delivery Systems Using Some Novel Penetration Enhancement Techniques - A Critical Review, International Journal of Life Science and Pharma Research, November 2023, International Journal of Pharma and Bio Sciences,
DOI: 10.22376/ijlpr.2023.13.6.p51-p77.
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