The First Decade of Advanced Cell Therapy Clinical Trials using Cord Blood and other Perinatal Cells

What is it about?

Perinatal cells refer to cells that come from the various components of the after-birth: Umbilical cord blood, umbilical cord tissue, the placenta and amniotic membrane, etc. The perinatal blood and tissues are rich in various types of stem and progenitor cells. Cells from perinatal sources are increasingly used for regenerative medicine and immunotherapy. In our paper we review the first decade of clinical trials that employ perinatal cells for advanced cell therapy.

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Why is it important?

Cells from perinatal sources were first used in regenerative medicine in 2005. This paper is important because it is the first review of regenerative medicine clinical trials with perinatal cells, covering the initial decade 2005 - 2015.