What is it about?

Short-time exposure to a SiC nanoaerosol, resulted in unexpected fast clearance times from rat lungs (contrary to expected lung particle overload). Such clearance was found asymmetric and non-homogenous with respect to lung tissue, according to µPIXE 2D maps analysis.

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Why is it important?

This nonhomogenous clearance pattern in lung and other tissues may be regulated by physicochemical properties of nanoparticles.

Perspectives

This work sets an avenue of research for more fine detail biopersistence models of nanoparticles different tissues. Such work should be of great use for the nanotoxicology and nanomedicine communities.

Dr OMAR LOZANO
Instituto Tecnologico y de Estudios Superiores de Monterrey

Read the Original

This page is a summary of: Fast, asymmetric and nonhomogeneous clearance of SiC nanoaerosol assessed by micro-particle-induced x-ray emission, Nanomedicine, November 2017, Future Medicine,
DOI: 10.2217/nnm-2017-0245.
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