Central neurotoxicity induced by the instillation of ZnO and TiO2 nanoparticles through the taste nerve pathway

What is it about?

There are no published reports on whether NPs can be transported into the CNS via the taste nerve pathway. In this study, ZnO NPs and TiO2 NPs can be taken up by taste buds after tongue instillation for 30 days, then translocated to the NST, parabrachial nucleus, thalamic nucleus, ultimately accumulating in the gustatory cortex after exposure to tongue instillation.

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