What is it about?
Old DNA reduces DNA methylation and accumulate DNA lesions. Alu- siRNA increases DNA methylation at Alu elements and reduces DNA lesions.
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Why is it important?
This may be a new hope to prevent or event reverse aging process.
Perspectives
Future research in animal experiments will demonstrate applications in human. Hopefully to prevent or correct disability in aging.
Apiwat Mutirangura
Chulalongkorn University
Read the Original
This page is a summary of: Alu siRNA to increase Alu element methylation and prevent DNA damage, Epigenomics, January 2018, Future Medicine,
DOI: 10.2217/epi-2017-0096.
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