What is it about?
This is a review article that covers new insights into the causes of primary membranous nephropathy, the recently discovered biologic mechanisms involved in producing kidney injury and disease and the approaches to treatment that target those mechanisms and produce the best outcomes as documented in clinical trials.
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Why is it important?
Membranous nephropathy is the most common cause of nephrotic syndrome (high levels of protein leaking from the kidney into the urine) in adults. How we understand the mechanisms that cause this disease has been transformed in the past decade. These new mechanisms will likely shed light on how other diseases of the kidney are caused. This review covers the new research findings that clarify how kidney glomeruli are injured in this disease and the approaches to treatment that are now used based on the newer findings.
Read the Original
This page is a summary of: Primary Membranous Nephropathy, Clinical Journal of the American Society of Nephrology, May 2017, American Society of Nephrology, DOI: 10.2215/cjn.11761116.
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