What is it about?
Representation of chromium metal compounds that showed antimicrobial activity against several bacteria, gram positive and negative.
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Why is it important?
Due to bacterial resistance to antibiotics it is necessary to find new ways to inhibit microbes activity.
Perspectives
Nowadays, one of the greatest challenges that scientists are facing is the resistance that several bacteria developed over the established antibiotics. Novel compounds should be developed and evaluated against different bacterial. Metal-based drugs are among the most promising compounds that can be used in that direction. Based on this review, metal coordination to several ligands improved the antimicrobial activity of metals or ligands dramatically. Cr(III)- complexes seem to present a very promising antimicrobial activity against several bacteria. Sometimes the antimicrobial activity of Cr(III)-complexes was comparable or better than that of clinical drugs.
Dr Manos C. Vlasiou
University of Nicosia
Read the Original
This page is a summary of: Chromium Coordination Compounds with Antimicrobial Activity: Synthetic Routes, Structural Characteristics, and Antibacterial Activity, The Open Medicinal Chemistry Journal, June 2020, Bentham Science Publishers,
DOI: 10.2174/1874104502014010001.
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