What is it about?

This overview showed that severe infection of SARS-CoV-2 during the early stage of pregnancy might increase the risk of stress, panic, and anxiety. This disorder can disturb the maternal immune system, and thus causing a neurodevelopmental disturbance. This hypothesis may be depending on the severity and intensity of the SARS-CoV-2 infection during pregnancy. However, vertical transmission of SARS-CoV-2 from dams to their fetuses is absent until now.

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Why is it important?

- Vertical transmission of SARS-CoV-2 from dams to their fetuses is absent until now. - In severe states, SARS-CoV-2 can increase the risk of maternal stress and fever. - COVID-19 disease can disrupt maternal immunity and neonatal neurogenesis. - Symptoms of SARS-CoV-2 may be depending on its severity & intensity during pregnancy. - This review suggested some control strategies like treatment, nutrition uptake, prevention, and recommendations.

Perspectives

SARS-CoV-2 infection during the early stage of pregnancy may increase the risk of stress, panic, anxiety, and fever states. This disturbance can perturb the maternal immunity and neonatal neurogenesis. This hypothesis may be depending on the severity and intensity of the SARS-CoV-2 infection during pregnancy (Figure 1). Because pregnancy is a unique period for a woman's life, more healthcare, protection, nutrition uptake, and proper awareness are required during this global pandemic disease. Thus, additional research and clinical studies are needed to highlight these issues and addressed the impact of maternal COVID-19 disease on neonatal immunity and cognitive behavior.

Full Professor Ahmed R. G.
Division of Anatomy and Embryology, Zoology department, Faculty of Science, Beni-Suef University, Egypt.

Read the Original

This page is a summary of: Novel Coronavirus SARS-CoV-2 (COVID-19) and Pregnancy: A Hypothetical View, Endocrine Metabolic & Immune Disorders - Drug Targets, October 2021, Bentham Science Publishers,
DOI: 10.2174/1871530320666201023124843.
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