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Despite a number of innovations in anti-diabetic drugs and substantial improvement in diabetes care, the number of people with diabetes continues to increase, suggesting further need to explore novel approaches to prevent diabetes. This paper summarizes recent evidence showing the importance of beta cell dysfunction in T2DM and refines the “beta cell workload hypothesis”, emphasizing the importance of beta cell preservation for the prevention and management of T2DM.

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This page is a summary of: Changing the Concept of Type 2 Diabetes: Beta Cell Workload Hypothesis Revisited, Endocrine Metabolic & Immune Disorders - Drug Targets, August 2018, Bentham Science Publishers,
DOI: 10.2174/1871530318666180821161825.
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