What is it about?
it is about MDR and new compounds of 1,4-dihydropyridine (DHP) were recommended as inhibitors of P-gp.
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Why is it important?
it is important for treatment of cancer
Perspectives
Racemic asymmetric compounds with R and S enantiomers have the potential for enantiomeric separation. Each of these enantiomers could have a different physiological effect. suggestion for designing and synthesis of new anticancer drugs.
maryam iman
Baqiyatallah University of Medical Sciences
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This page is a summary of: Synthesis and DFT Study on Hantzsch Reaction to Produce Asymmetrical Compounds of 1,4-Dihydropyridine Derivatives for P-Glycoprotein Inhibition as Anticancer Agent, Recent Patents on Anti-Cancer Drug Discovery, May 2018, Bentham Science Publishers,
DOI: 10.2174/1574892813666180220112613.
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