What is it about?

The research is regarding the pharmacological efficacy of certain synthesized moieties of Isatin to attenuate depression which is the major and leading cause of mortality nowadays.

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Why is it important?

We define the prediction of ADMET analysis and toxicity studies computationally and the lead moieties passed in the Lipsinki rule of 5 are further taken into molecular docking studies.

Perspectives

The importance of this work is the social concern to elucidate the anti depressant medications to overcome the mood disorders.

Muthukumaran Thulasingam
Dayananda Sagar Institutions

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This page is a summary of: Docking, Synthesis, and In vitro Anti-depressant Activity of Certain Isatin Derivatives, Current Computer - Aided Drug Design, October 2024, Bentham Science Publishers,
DOI: 10.2174/1573409919666230523114134.
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