What is it about?
The study aimed to evaluate the in silico binding of some promising benzofurans on the GABA receptors, and the in vivo neurotropic activity of benzofuran analogues (BZF 6-10) of gamma-aminobutyric acid (GABA) on a seizure model.
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Why is it important?
Results suggest that some benzofurans are GABAergic antagonists with stimulatory activity on the CNS
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This page is a summary of: Synthesis and Biological Evaluation of Novel 2,3-disubstituted Benzofuran Analogues of GABA as Neurotropic Agents, Medicinal Chemistry, January 2019, Bentham Science Publishers,
DOI: 10.2174/1573406414666180524091745.
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