What is it about?
he increasing number of people living with Alzheimer’s disease (AD) constitutes a growing global concern. At present, nearly 44 million people suffer from AD worldwide, and these numbers are expected almost to double every 20 years. Given its high prevalence and growing incidence, AD is one of the top causes of disabilities in later life, and this takes an enormous toll on the caregivers. Importance: It is tremendously important to explore new ways of an understanding AD, as this may improve the management of this growing medical, socio-economic, and public health care burden.
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Why is it important?
Evidence suggests that AD may evolve through the unique process of ‘retro-genesis’; a decline that mirrors, in reverse order, brain development that occurs from birth. The retro-genesis hypothesis distinguishes distinct stages, each one linked to levels of cognitive functioning in developing children.
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This page is a summary of: The Retrogenesis Model in Alzheimer’s Disease: Evidence and Pract ical Applications, Current Psychiatry Reviews, July 2017, Bentham Science Publishers,
DOI: 10.2174/1573400513666170127093925.
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