What is it about?

The current review discusses the various conventional drugs, herbal drugs, combination therapy and the use of nutraceuticals for the effective management of diabetes mellitus. The biotechnological aspects of various antidiabetic drugs are also discussed.

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Why is it important?

Oral antihyperglycemics which are used to treat diabetes can cause many adverse effects and if given in combination can lead to drug-drug interactions. The combination of various phytochemicals with synthetic drugs can overcome the challenge faced by the synthetic drug treatment. Herbal and nutraceuticals therapy and the use of probiotics and prebiotics is a more holistic therapy due to its natural origin and traditional use.


More than 170 papers including both, research and review articles, were included in this review in order to produce a comprehensive as well as readily understandable article. A series of herbal and synthetic drugs have been discussed along with their current status of treatment in terms of dose, mechanism of action and possible side effects. The article also focuses on combination therapies containing synthetic as well as herbal drugs to treat the disease. The role of pre and probiotics in management of diabetes is also highlighted.

Dr Pranav Kumar Prabhakar
Lovely Professional University

Read the Original

This page is a summary of: A Systematic Review on Synthetic Drugs and Phytopharmaceuticals Used to Manage Diabetes, Current Diabetes Reviews, April 2020, Bentham Science Publishers, DOI: 10.2174/1573399815666190822165141.
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