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It was found that the position of hydroxy and methoxy groups in new analgesics determines the mechanism of their action.

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Why is it important?

Very small changes in structures of terpene-derived compounds fully changes the mechanisms of their biological activity.

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This page is a summary of: The Decisive Role of Mutual Arrangement of Hydroxy and Methoxy Groups in (3(4)-hydroxy-4(3)-methoxyphenyl)-4,7-dimethyl-3,4,4a,5,8,8ahexahydro- 2H-chromene-4,8-diols in their Biological Activity, Letters in Drug Design & Discovery, April 2017, Bentham Science Publishers,
DOI: 10.2174/1570180813666161102142642.
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