What is it about?

We achieved PMA-SiO2 catalysed synthesis of 1,8-dioxodecahydroacridines through multi component reactions (MCRs) of 5, 5-dimethylcyclohexane-1, 3-dione, aldehydes and anilines in PEG- 400. Moreover, varieties of dioxodecahydroacridine derivatives were also synthesized in good yields by using PMA-SiO2 catalyst.

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Why is it important?

A simple method using reusuable catalysts

Perspectives

This study can provide a road map to design new green synthetic methodologies for single step cyclo-condensation reaction through MCRs with better yields

Prabhakara Rao Koya
Vignan Educational Foundation

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This page is a summary of: A Facile, Efficient and Convenient Synthesis of 1,8-Dioxodecahydroacridines with PMA-SiO2 Reusable Catalyst, Letters in Organic Chemistry, October 2018, Bentham Science Publishers,
DOI: 10.2174/1570178615666180212153735.
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