What is it about?
#1. How Streptozotocin produce hyperglycemia via inducing oxidative stress ? #2. How the flavonid mixture reduce above effects in an in vivo model? #3. Few apoptosis/necrosis signaling pathways are discussed.
Featured Image
Why is it important?
Extremely relevant clinically to diabetics; these patients can consume select fruits and vegetable rich in these polyphenolic flavonoids and reduce blood sugar ( may be A1C??). By no means this is a 'magic bullet' mixture to bring A1C down but exposure to these in addition to many other may help control blood sugar.
Perspectives
Mixture of select phytochemicals are likely to be more potent compared to single entities. In addition, these phytoextracts have hepato-, nephro-, neuro-, and cardioprotective activities.
Dr SIDHARTHA D RAY
Touro College
Read the Original
This page is a summary of: Curcumin, Hesperidin, and Rutin Selectively Interfere with Apoptosis Signaling and Attenuate Streptozotocin-Induced Oxidative Stress- Mediated Hyperglycemia, Current Neurovascular Research, September 2015, Bentham Science Publishers,
DOI: 10.2174/1567202612666150812150249.
You can read the full text:
Contributors
The following have contributed to this page
