What is it about?
Nanoparticulation is a new method of drug delivery which provides a safer and more effective way for treating cancers and other diseases. We explained the benefits and the mechanisms in which participate in this model of targeted therapy. Additionally, we provided examples and explained how nanoparticulation affects pharmacodynamics of drugs.
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Why is it important?
Our review showed that nanoparticulation can change the expected effects of drugs which can be helpful or dangerous. Putting this concept in mind warrants the fact that the designation and composition of nanoparticulated drugs is extremely important to achieve the most favorable result and the effect of nanoparticle itself or in combination with the drug should be examined before marketing.
Perspectives
I wish this article shows a future path to design and produce more effective nanoparticles. This article can expand our knowledge about the effects of nanoparticles on human body however, previous articles focused on the effect of human body on nanoparticles.
Moein Ala
Tehran University of Medical Sciences
Read the Original
This page is a summary of: Do pharmacodynamics of drugs change after presenting them as nanoparticles like their pharmacokinetics?, Current Drug Targets, January 2020, Bentham Science Publishers,
DOI: 10.2174/1389450121666200128113547.
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