What is it about?
MRP-2 is a protein responsible for resistance towards anticancer and antimicrobial drugs. Here we developed a model based on machine learning which can predict whether a new molecule will be a substrate of MRP-2 or not.
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Why is it important?
The dataset used for making prediction model in this study is highly validated and cross-checked
Perspectives
I hope this article will help in the early stages of drug discovery so that the lead compounds which might be the substrate of MRP-2 can be removed from the lead library
Hardeep Sandhu
National institute of pharmaceutical education and research, S.A.S. Nagar
Read the Original
This page is a summary of: Predicting Inhibitors for Multidrug Resistance Associated Protein-2 Transporter by Machine Learning Approach, Combinatorial Chemistry & High Throughput Screening, December 2018, Bentham Science Publishers,
DOI: 10.2174/1386207321666181024104822.
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