What is it about?
Agaricus blazei Murrill (ABM) is a Brazilian mushroom popularly known as the sun mushroom. It is widely used today in several Oriental countries both as an edible mushroom, considered as functional food, and for therapeutic purposes. This paper examines the past decade findings related to biotechnological, nutritional and therapeutic uses of A. blazei, with special emphasis on the most recent discoveries regarding its chemical composition. The main isolated and identified compounds or fractions are described and confronted with their corresponding bioactivities.
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Why is it important?
The amount and quality of the evidence that has been accumulating during the last decade strongly speaks in favor of the health benefits of the ingestion of A. blazei or derived products. However, there are many uncertainties and limitations when attempts are made to extrapolate or to demonstrate their biological effects in the human organism in health or disease. Clearly, more clinical trials, using reliable statistical methods and standardized preparations are needed to establish the efficacy of A. blazei as a therapeutic agent.
Perspectives
It was highly rewarding to me to write this article because as work progressed it became clear to me, with reference to the medicinal properties of Agaricus blazei, that vox populi can be sometimes very wise to the point that it is truly transformed into a kind of vox sapientis. This, of course, requires serious investigations that I had the immense pleasure of summarizing to the scientific community.
Rosane Peralta
Read the Original
This page is a summary of: Agaricus blazei Bioactive Compounds and their Effects on Human Health: Benefits and Controversies, Current Pharmaceutical Design, July 2017, Bentham Science Publishers,
DOI: 10.2174/1381612823666170119093719.
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