What is it about?
A review of prepared analogues of thapsigargin and their calcium pump inhibitory activity
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Why is it important?
Thapsigargin is and important standard in research concerning calcium homeostasis and the starting point for new chemotherapeutics.
Perspectives
The review might inspire to develop new agents either for use as drugs or for better understanding of calcium homeostatsis.
Professor Søren Brøgger Christensen
University of Copenhagen
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This page is a summary of: Thapsigargin, Origin, Chemistry, Structure-Activity Relationships and Prodrug Development, Current Pharmaceutical Design, November 2015, Bentham Science Publishers,
DOI: 10.2174/1381612821666151002112824.
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