What is it about?
Human immunodeficiency virus (HIV) is a significant cause of morbidity and mortality worldwide. HIV patients commonly suffer from various hematological abnormalities. This study evaluated bone marrow changes in 20 HIV-positive patients over one year at a tertiary care hospital, providing a comprehensive overview of the hematological changes associated with HIV infection.
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Why is it important?
The study highlights the importance of bone marrow examination, along with clinical history and other investigations, in identifying peripheral hematological abnormalities, opportunistic infections and malignancies in HIV patients. Key findings include- Most common hematological abnormality on peripheral smear was anemia (90%), with Microcytic hypochromic anemia being the predominant type. The bone marrow was hypercellular in 70% of cases, while dysplasia was noted in 60% of cases. Erythroid hyperplasia and Erythroid normoblastic maturation were the most frequently observed findings among HIV-infected patients. Reactive changes associated with HIV were also observed and reported. Additionally, one patient had autoimmune hemolytic anemia and another had visceral Leishmaniasis associated with HIV.
Perspectives
This article highlights the importance of bone marrow examination in early diagnosis which helps in better patient management and timely treatment, improving patient outcomes.
vanita rathi
Read the Original
This page is a summary of: Study of Bone Marrow Findings in Human Immunodeficiency Virus (HIV) Positive Patients in a Tertiary Care Hospital, Cardiovascular & Haematological Disorders - Drug Targets, August 2026, Bentham Science Publishers,
DOI: 10.2174/011871529x400898251018183038.
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