What is it about?
In Liquisolid systems, the liquid medication is absorbed into the interior framework of carriers. Once the carrier's interior is saturated with liquid medication, a liquid layer forms on the surface of the carrier particles, which is instantly adsorbed by the fine coating material. As a result, a dry, free-flowing, and compressible powder mixture is formed
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Why is it important?
Compared to other solubility enhancement techniques, s.a. micronization, inclusion complexation, microencapsulation, nanosuspension, and self-nano emulsions, LST is relatively simple to prepare and may offer a cost-effective solution to enhance the solubility of poorly water-soluble drugs enhancing its bioavailability in drug formulation and delivery.
Perspectives
Current Drug Discovery Technologies is an essential journal for all scientists and research managers involved in drug discovery who wish to keep abreast of all the modern techniques and technologies used in drug discovery.
Dr. Amaresh Prusty
Royal College of Pharmacy and Health Sciences
Read the Original
This page is a summary of: Liquisolid Technique for Solubility Enhancement of Poorly Soluble Drug - A Brief Review, Current Drug Discovery Technologies, October 2024, Bentham Science Publishers,
DOI: 10.2174/0115701638318659240923074614.
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