What is it about?
Indole is a crucial scaffold in drug discovery, with many indole derivatives exhibiting diverse pharmacological activities.
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Why is it important?
This review article highlights promising compounds and synthetic strategies. Other scientist can use it as a roadmap to develop better drugs so instead of reading dozens of paper, readers get a concise overview in one place.
Perspectives
Exploring indole-based compounds has deepened my appreciation for how small structural changes can lead to significant biological impacts. Writing this review allowed me to reflect on the remarkable versatility of the indole scaffold in drug discovery. I hope it inspires further research and innovation in medicinal chemistry, especially in the areas of synthesis and structure–activity relationships.
Mebantei Janai Bang
University of science and technology, Meghalaya
Read the Original
This page is a summary of: Insights into the Synthesis and Bioactivity of Indole-Based Compounds: A Short Review, Current Organic Chemistry, July 2025, Bentham Science Publishers,
DOI: 10.2174/0113852728382848250610051815.
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