What is it about?
This review explores encouraging novel pharmacological avenues for major depressive disorder treatment. These include targeting receptors, such as N-methyl-D-aspartate and metabotropic glutamate receptors, and employing glutamatergic modulators and various augmentation strategies, all of which hold the potential for reversal of depressant effects.
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Why is it important?
Combining innovative concepts with enhancements of existing discoveries may propel antidepressant research forward, offering hope for developing compounds that are effective and rapid in their action, even among patients who have found limited success with other therapies.
Perspectives
This review explores the recent advances and treatment strategies to mitigate depressive disorder.
Muthukumaran Thulasingam
Dayananda Sagar Institutions
Read the Original
This page is a summary of: Exploring New Frontiers in Pharmacological Treatment of Depression: A Review on Recent Advances, Current Medicinal Chemistry, May 2025, Bentham Science Publishers,
DOI: 10.2174/0109298673342524250109181220.
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