Nanomedical Devices and Cancer Theranostics

  • Mohamed Moumaris, Jean-Michel Bretagne, Nisen Abuaf
  • The Open Nanomedicine and Nanotechnology Journal, April 2020, Bentham Science Publishers
  • DOI: 10.2174/2666150002006010001

Photo by National Cancer Institute on Unsplash

Photo by National Cancer Institute on Unsplash

What is it about?

The current therapies against cancer showed limited success. Nanotechnology is a promising strategy for cancer tracking, diagnosis, and therapy. The hybrid nanotechnology assembled several materials in a multimodal system to develop multifunctional approaches to cancer treatment. The quantum dot and polymer are some of these hybrid nanoparticle platforms. The quantum dot hybrid system possesses photonic and magnetic properties, allowing photothermal therapy and live multimodal imaging of cancer. These quantum dots were used to convey medicines to cancer cells. Hybrid polymer nanoparticles were utilized for the systemic delivery of small interfering RNA to malignant tumors and metastasis. They allowed non-invasive imaging to track in real-time the biodistribution of small interfering RNA in the whole body. They offer an opportunity to treat cancers by specifically silencing target genes. This review highlights the major nanotechnology approaches to effectively treat cancer and metastasis.

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