What is it about?
Glaucoma is one of the leading causes of irreversible blindness globally and directly impacts optic nerve-altering vision. The condition has been linked to increased intraocular pressure (IOP). The objective of this review was to search at how well different drug solutions containing gold nanoparticles (GNPs) work in treating glaucoma, with a focus on using contact lenses instead of regular eye drops.
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Why is it important?
The review found that timolol helps reduce intraocular pressure for the first two hours, but then the effect wears off. Moreover, gold nanoparticles infused with timolol solution on contact lenses improved IOP. GNPs in lenses increased the accumulation of timolol in ciliary muscles.
Perspectives
Contact lenses with saturated drug solutions and GNPs have better bioavailability and release durations. Given its prolonged drug release time and bioavailability, the timolol solution relieves intraocular pressure better than other solutions. GNP-infused contact lenses with drug solutions treated glaucoma better than eye drops.
Hassan Aljaberi
Dijlah University College
Read the Original
This page is a summary of: Contact Lens as Drug Delivery System for Glaucoma Treatment: A Review, The Open Ophthalmology Journal, March 2023, Bentham Science Publishers,
DOI: 10.2174/18743641-v17-e230214-2022-36.
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