What is it about?

Amyloid beta is an specific protein that is produced in the brain. When amyloid beta production is not tightly related, it damages the brain. One of the ways by which amyloid beta is able to damage the brain cells is through the impairment of mitochondria, a part of the cell that produces energy and mantain brain cells healthy. In this work we aim to summarize the mechanisms by which amyloid beta impairs brain mitochondria, a phenomenon that can be related to the origin of several brain disorders, such as Alzheimer's disease.

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Why is it important?

This work is important because the number of people with Alzheimer's disease is increasing drastically, and modern medicine is still not able to find a cure or medicine that can treat this disease. Therefore, studying the mechanisms that can lead to this disease could help us to understand it better and eventually be able to increase the lifespan and life quality of the patients of this disease.

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This page is a summary of: Amyloid Beta Peptide-Mediated Alterations in Mitochondrial Dynamics and its Implications for Alzheimer’s Disease, CNS & Neurological Disorders - Drug Targets, August 2023, Bentham Science Publishers, DOI: 10.2174/1871527321666220616094036.
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