What is it about?
Cancer is on the rise worldwide. On the other hand, the present treatments such as chemotherapy and radiation therapy are associated with many side effects. In this study, we have shown for the firs time, that the active ingredient in Cinnamon can fight cancer cells. In other words, a cell that has active oncogenes is a good target for treatment with this plant without damaging to normal cells.
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Why is it important?
Our results show that the Cinnamaldehyde, which is the main active ingredient in Cinnamon, can have inhibition effect on the main and important oncogenes involved in cancer. On the other hand, we have shown that Cinnamaldehyde disrupts the link between an important protein called HSF1 and the cancer cell metabolism previously seen, and that it accurately targets cancer cells without damaging normal cells. Cinnamaldehyde By acting on the sensitive points of the cell's life, kills it.
Perspectives
This study is applied two ways. First, Cinnamon has long been used as a spice as well as a fragrance in communities. Therefore, its use will be desirable for patients. Second, given its role in the important cancer signaling studied in this study, it can be a good target for cancer treatment.
Dr zeynab aminzadeh
Department of Clinical Biochemistry
Read the Original
This page is a summary of: Anticancer Effects of Cinnamaldehyde Through Inhibition of ErbB2/HSF1/LDHA
Pathway in 5637 Cell Line of Bladder Cancer, Anti-Cancer Agents in Medicinal Chemistry, April 2022, Bentham Science Publishers,
DOI: 10.2174/1871520621666210726142814.
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