What is it about?

Patients with rheumatoid arthritis (RA) often suffer anxiety and depression. Proinflammatory cytokines are elevated in RA. Other cofactors may influence the systemic inflammation process in RA patients presenting with anxiety and depression symptoms. The proinflammatory cytokines were elevated in active state of RA. However, no link was found between this inflammatory state and rheumatoid arthritis patients with anxiey and depression symptoms.

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Why is it important?

Rheumatoid arthritis (RA) patients often experience anxiety and depression symptopms. Exploring the potential mechanisms of these symptoms are required to start the treatment. By knowing the clear pathophysiology of these symptoms in rheumatoid arthritis, clinical physicians may start the proper treatment. Therefore, the compliance treatment and prognosis of these patients may be optimal.


I was excited to write and submit this reasearch study. I hope the readers may feel the benefits of reading this article. This article help me to treat the RA patients presenting with mental illness symptoms.

Faisal Parlindungan
Universitas Indonesia

Read the Original

This page is a summary of: Association between Proinflammatory Cytokines and Anxiety and Depression Symptoms in Rheumatoid Arthritis Patients: A Cross-sectional Study, Clinical Practice and Epidemiology in Mental Health, June 2023, Bentham Science Publishers, DOI: 10.2174/17450179-v19-e230510-2022-34.
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