What is it about?

BLAST search allows us to find similar protein sequences for a given protein. SimExact allows to serach proteins having similar functions to given protein in an efficient way.

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Why is it important?

If existing semantic similarity methods are used, searching for similar proteins from a large database would take longer time, making it practically not possible. SimExact makes it possible in reasonable time (few seconds).

Perspectives

During experimentation, I found some thing interesting in Gene Ontology and protein annotations. Based on that, I proposed this method for fast searching the related proteins. This can lead to do unique analyses, which were not possible before.

Najmul Ikram
COMSATS University Islamabad Wah Campus

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This page is a summary of: SimExact – An Efficient Method To Compute Function Similarity Between Proteins Using Gene Ontology, Current Bioinformatics, October 2019, Bentham Science Publishers, DOI: 10.2174/1574893614666191017092842.
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